A wide range of applications and case-studies
- Biological clocks to monitor biological aging, associated disease, and the impact of intervention
- A high-resolution overview of expression, translatome and proteome diversity and its impact in health and disease
- The eQTL based identification of genetic variation explaining phenotypic differences
- The identification of causally dysregulated genes and biomarkers in disease (cancer, cardiovascular, …)
- Mapping transcriptional networks to identify key genes driving early mammalian development
Expertise in the analysis of a wide range of omics data
- Arrays, second and third generation sequencing for (epi)genomics, transcriptomics and ribosome profiling
- Proteomics by mass spectrometry and arrays
- Single-cell transcriptomics and multi-omics
Innovative data-analytical methods
- Allele-specific expression models for eQTL screening, genomic imprinting, early dysregulation in disease
- Machine-learning based characterization of the full complexity of RNA expression and protein translation
- Epigenetic and proteomics clocks of biological aging
- Biological clocks to monitor biological aging, associated disease, and the impact of intervention
- A high-resolution overview of expression, translatome and proteome diversity and its impact in health and disease
- The eQTL based identification of genetic variation explaining phenotypic differences
- The identification of causally dysregulated genes and biomarkers in disease (cancer, cardiovascular, …)
- Mapping transcriptional networks to identify key genes driving early mammalian development
Expertise in the analysis of a wide range of omics data
- Arrays, second and third generation sequencing for (epi)genomics, transcriptomics and ribosome profiling
- Proteomics by mass spectrometry and arrays
- Single-cell transcriptomics and multi-omics
Innovative data-analytical methods
- Allele-specific expression models for eQTL screening, genomic imprinting, early dysregulation in disease
- Machine-learning based characterization of the full complexity of RNA expression and protein translation
- Epigenetic and proteomics clocks of biological aging
- Arrays, second and third generation sequencing for (epi)genomics, transcriptomics and ribosome profiling
- Proteomics by mass spectrometry and arrays
- Single-cell transcriptomics and multi-omics
Innovative data-analytical methods
- Allele-specific expression models for eQTL screening, genomic imprinting, early dysregulation in disease
- Machine-learning based characterization of the full complexity of RNA expression and protein translation
- Epigenetic and proteomics clocks of biological aging
- Allele-specific expression models for eQTL screening, genomic imprinting, early dysregulation in disease
- Machine-learning based characterization of the full complexity of RNA expression and protein translation
- Epigenetic and proteomics clocks of biological aging